Apresentado no CROI 2018 (Conferência em Retrovírus e Infeções Oportunistas) este estudo demonstra que o enfarte de miocárdio pode ser reduzido com a substituição do abacavir.

Várias directrizes, como as britânicas, já recomendam a não utilização do abacavir em pessoas com risco elevado de doença cardiovascular.

Encontre o estudo em:

http://www.croiconference.org

1. Mallon P et al. Platelet function upon switching to TAF vs continuing ABC: a randomized substudy. 25th CROI, 4-7 March 2018, Boston. Oral abstract 80.
   www.croiconference.org/sessions/platelet-function-upon-switching-taf-vs-continuing-abc-randomized-substudy (abstract)
   www.croiwebcasts.org/console/player/37179 (webcast)
2. Mallon P et al. Change in soluble glycoprotein VI (SGPVI) when switching from ABC/3TC to TAF/FTC. 25th CROI, 4-7 March 2018, Boston. Poster abstract 677LB
   www.croiconference.org/sessions/change-soluble-glycoprotein-vi-sgpvi-when-switching-abc3tc-tafftc (abstract and poster)
3. Kirk A Taylor et al. Comparative impact of antiretrovirals on human platelet activation. 25th CROI, 4-7 March 2018, Boston. Poster abstract 673.
   www.croiconference.org/sessions/comparative-impact-antiretrovirals-human-platelet-activation (abstract and poster)
4. Victor Collado-Diaz. Leukocytes are key to the pro-thrombotic effects of abacavir. 25th CROI, 4-7 March 2018, Boston. Poster abstract 674.
   www.croiconference.org/sessions/leukocytes-are-key-pro-thrombotic-effects-abacavir (abstract and poster)
5. Hsue P et al. Comparing strategies for reducing myocardial infarction rates in HIV patients. 25th CROI, 4-7 March 2018, Boston. Poster abstract 692.
   www.croiconference.org/sessions/comparing-strategies-reducing-myocardial-infarction-rates-hiv-patients (abstract and poster)

Artigo inicialmente publicado por HIV i-base.